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"In 1953, James Watson and Francis Crick discovered the double helix structure of DNA. The discovery was a profound, Nobel-Prize-winning moment in the history of genetics, but it did not decipher the messages on the twisted ladderlike strands within our cells. No one knew what the human genome sequence actually was. No one had cracked the code of life. Now, at the beginning of a new millennium, that code has been cracked ... Here for the first time,...
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Completion of the Human Genome Project will make possible a staggering array of new medical technologies, including new diagnostic and screening tests for inherited disorders, gene therapies, and the ability to manipulate a person's inherited, non-disease traits. Most of the attention given to the social implications of these technologies has focused on their potential to harm the individual, for example, by denying employment or insurance. This book...
Description
This documentary examines the complex race to decode the human genome. Examines the work of, and contains interviews with: Francis Collins, director of the National Center for Human Genome Research; J. Craig Venter, head of its rival, the private Celera Genomics; and the Whitehead Institute's Eric Lander, one of the leaders of the Human Genome Project.
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"Welcome to the Genome takes you right into the thick of today's most cutting-edge science and its far-reaching implications. Authors Rob DeSalle and Michael Yudell have written a book which clearly explains the ongoing saga of our attempts to understand the mystery of biology's Rosetta Stone and use its code to better our lives." "This book employs an understandable style and full-color illustrations to provide insights into the complex science involved....
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"The Human Blueprint is an exciting and readable description of one of the greatest scientific enterprises of all time, the sequencing of the human genome. Robert Shapiro authoritatively tells us both what scientists are doing and some of the likely social implications of their work. His book will be of great interest to anyone who wishes to know about the shape of things to come," Gerald Feinberg, Columbia University, Professor of Physics.
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The human genome, the complete set of genes housed in twenty-three pairs of chromosomes, is nothing less than an autobiography of our species. Spelled out in a billion three-letter words using the four-letter alphabet of DNA, the genome has been edited, abridged, altered and added to as it has been handed down, generation to generation, over more than three billion years. With the first draft of the human genome due to be published in 2000, we, this...
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"John Sulston was director of the Sanger Centre in Cambridge from 1993 to 2000. There he led the British arm of the international team selected to map the entire human DNA sequence, a feat that was pulled off in record time by an extraordinary collaboration of scientists. The ultimate success of the project, after innumerable setbacks and challenges from outside competitors, can be attributed in large part to John Sulston's own determination, passion...
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"With stem cell research, Dolly the cloned sheep, in vitro fertilization, age retardation, and pharmaceutical mind enhancement, humankind is now faced with decisions that it has never before had to consider. The thoughtfulness, or lack of it, that we bring to those decisions will largely determine the future character of the living world. Brutes or Angels will facilitate informed choice making about the personal use of biotechnologies and the formulation...
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The Lives to Come is at once a concise and accessible guide to the research that scientists are conducting in the field of genetics, a realistic survey of the likely near-term contributions of that research to the treatment of disease, and a thoughtful probing of the deep moral and social issues raised by our increasing abilities to predict the onset of hereditary disease and to make decisions about the kinds of people who will be born. A distinguished...
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As the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way ... but the emerging picture is if anything far more exciting. Parrington gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating...
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"What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pääbo's mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009. From Pääbo, we learn how Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the...
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"In the age of global biotechnology, DNA can exist as biological material in a test tube, as a sequence in a computer database, and as economically valuable information in a patent. In The Global Genome, Eugene Thacker asks us to consider the relationship of these three entities and argues that - by their existence and their interrelationships - they are fundamentally redefining the notion of biological "life itself.""--Jacket.
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The book examines how sophisticated tools of genetic analysis and manipulation are being developed in laboratories all over the world and considers the impact they will have on issues that scientists consider, including the causes of aging and death, the nature of the brain, and quality of life. Drawing from many research streams-such as advances in molecular and cell biology, imaging, and informatics-genetics is shown to encompass a view of nature...
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