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"Biomedical science--the research that underlies our treatments and cures--is in deep crisis. Every year, American taxpayers spend more than $30 billion funding it. About half of that work, by some estimates, is wrong. As award-winning science journalist Richard Harris reveals in Rigor Mortis, this is not simply the result of trial and error, which is an essential part of the scientific process. The economic imperative for researchers to get and keep...
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A medical thriller featuring Dr. Edward Armstrong, a researcher developing an anti-depressant drug. Under pressure from his backers to complete the research, he experiments on himself with disastrous effects. But with millions of dollars at stake, the backers hush up the results and when Armstrong's sweetheart, Kimberly Stewart, decides to blow the whistle, she puts both their lives in jeopardy. By the author of Fatal Cure.
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"In a brilliant, definitive history of one of the most significant and controversial medical events of modern times, [the author] brings to light a bizarre clash of scientific personoalities. When F.G. Banting and J.J.R. Macleod won the 1923 Nobel Prize for discovering and isolating insulin, Banting immediately announed that he was dividing his share of the prize with his young associate, C.H. Best. Macleod divided his share with a fourth member of...
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This book addresses the common criticisms of evidence-based healthcare, dispelling many of its myths and misconceptions, while providing a pragmatic framework for testing the validity of healthcare literature. It also helps readers to understand the central principles of evidence-based medicine, critically evaluate published data, and implement the results in practical settings. The readers are guided through each fundamental step of inquiry, from...
Description
This book brings together in one volume fifteen Nobel Prize-winning discoveries that have had the greatest impact upon medical science and the practice of medicine during the 20th century and up to the present time. Its overall aim is to enlighten, entertain and stimulate. This is especially so for those who are involved in or contemplating a career in medical research. Anyone interested in the particulars of a specific award or Laureate can obtain...
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Recent scandals and controversies such as the fabrication of data in federally funded science, the manipulation and distortion of research sponsored by private companies, human embryonic stem cell research, cloning, and the patenting of DNA and cell lines, illustrate the importance of ethics in scientific research.
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"Engineering has been an essential collaborator in biological research and breakthroughs in biology are often enabled by technological advances. Decoding the double helix structure of DNA, for example, only became possible after significant advances in such technologies as X-ray diffraction and gel electrophoresis. Diagnosis and treatment of tuberculosis improved as new technologies--including the stethoscope, the microscope, and the X-ray--developed....
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"This study examines how conflicts of interest have become pervasive, and explores the troubling state of research funding and flaws of the peer-review process. It looks in depth at the dominance of several specific theories, including the Big Bang cosmology, human-caused global warming, HIV as a cause of AIDS, and the efficacy of anti-depressant drugs"--
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Publisher description: Businesses that produce bioscience products?gene tests and therapies, pharmaceuticals, vaccines, and medical devices?are regularly confronted with ethical issues concerning these technologies. Conflicts exist between those who support advancements in bioscience and those who fear the consequences of unfettered scientific license. As the debate surrounding bioscience grows, it will be increasingly important for business managers...
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Description
Guides students in developing appropriate key skills when designing experiments, generating results, analysing data and ultimately presenting findings to academics and referees. Taking a hands-on approach, each of these key areas is introduced clearly and carefully, showing how to access and evaluate information using a variety of resources. Basic analytical theory is gradually introduced alongside practical applications to enhance student understanding....
Description
"The Ethics of Medical Testing: Modern Medical Testing Is Shaped by a Troubled Legacy; Strict Guidelines Ensure Safe and Ethical Medical testing on Humans; Medical Testing on Humans Can Be Dangerous and Corrupt; Review Boards Are Inadequate to Ensure Ethical Medical Testing; Medical Testing on Prisoners Is Unethical and Should Be Outlawed; Medical Testing on Prisoners Can Be Done Ethically; Medical Testing on Children Involves Unique Considerations;...
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"How do scientists develop new explanations of disease? How do those explanations become accepted as true? And how does medical diagnosis change when physicians are confronted with new scientific evidence? These are some of the questions that Paul Thagard pursues in this book that develops a new, integrative approach to the study of science." "How Scientists Explain Disease challenges both traditional philosophy of science, which has viewed science...
19) State of wonder
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Description
A researcher at a pharmaceutical company, Marina Singh journeys into the heart of the Amazonian delta to check on a field team that has been silent for two years-- a dangerous assignment that forces Marina to confront the ghosts of her past.
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"The fight against child mortality that transformed parenting, doctoring, and the way we live. Only one hundred years ago, even in the world's wealthiest nations, children died in great numbers-of diarrhea, diphtheria, and measles, of scarlet fever and meningitis. Culture was shaped by these deaths; diaries and letters recorded them, poets and writers from Louisa May Alcott to Eugene O'Neill wrote about and lamented them. Not even the high and mighty...
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