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In the decade from 1935-1945, while the Second World War raged in Europe, a new class of medicines capable of controlling bacterial infections launched a therapeutic revolution that continues today. The new medicines were not penicillin and antibiotics, but sulfonamides, or sulfa drugs. The sulfa drugs preceded penicillin by almost a decade, and during World War II they carried the main therapeutic burden in both military and civilian medicine. Their...
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The Nazis discovered it. The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. It was sulfa, the first synthetic antibiotic. Science writer Hager chronicles the history of the drug that shaped modern medicine. Sulfa saved millions of lives--among them those of Winston Churchill and Franklin Delano Roosevelt Jr.--but even more, it changed the way new drugs were developed, approved,...
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